This hospital stay is the fifth, I think, for Will since July. It might be the sixth. First there was a bacterial infection, then (they think) CMV pneumonia, then very low sats and fevers, then the line infection (which they now sort of think might have been sample contamination) and high-dose steroids for the chronic rejection episode, and now this. So fifth. The recent idea is that there must be something else going on in addition to all the recent infections that is causing Will to never quite recover and, in fact, keep getting sick.
So, they're doing a number of examinations to see if they can tell which parts of Will are infected. Head CT (normal), eye examination (normal), and lumbar punch to collect spinal fluid to test (fluid appears normal, but it's the lab tests that will really show what is what). The lumbar punch thing is an example of, really, how tough Will is. I am about in tears if I have to have an IV put in. Will just gets through it, whatever it is. I remember when he was being treated for Hodgkin's lymphoma and the oncologist said about one of his (many) bone marrow biopsies: "you could give a class in how to tolerate these."
The blood test for EBV was negative. This is very good, because in the past EBV has always be associated with lymphoma for Will. The blood test for Adenovirus also was negative (again, good). Will still has Adenovirus in his lungs, but because they didn’t find it in his blood, it makes them feel the infection is (1) less serious and/or (2) starting to be on the way out. Nonetheless, they may decide they need to treat for that too, depending. It can be a very serious infection in someone with a suppressed immune system. The IgG treatment is on hold for a day or so until they figure out what type of cyptococcus infection they are treating and whether Will will need amphotericin. The IgG puts some strain on the kidneys and they want to have all the room they can get to treat with amphotericin if they need to.
So, that's today's update. Will is stable, no fevers today/yesterday. Still on 3-4L of oxygen by nasal cannula, but they are hoping to start weaning down, if that is possible.